IL17A and neoplasm: As for the pathway enrichment analysis of differentially expressed genes between the two groups, some of the enriched pathways, such as the production of molecular mediators of immune response (Fig. 3A), complement activation38 (Fig. 3A), B cell receptor signaling pathway39 (Fig. 3A), cytokine-cytokine receptor interaction (Fig. 3B), IL-17 signaling pathway40 (Fig. 3B), were revealed to have complex relationships with TME and tumor immunity.