The multivariable analysis was adjusted using the maximum NEQ dose, admission type, antibiotic use < 1 h from sepsis, gender, weight, race, age, first ICU admission, SOFA, CCI, renal replacement therapy, congestive heart failure, atrial fibrillation, renal, liver, and coronary diseases, respiratory failure, heart rate, systolic BP, diastolic BP, MAP, respiratory rate, temperature, oxygen saturation, prothrombin time, activated partial thromboplastin time, international normalized ratio, and bicarbonate, blood urea nitrogen, sodium, chloride, potassium, and lactate levels. The gene discussed is F2; the disease is congestive heart failure.