The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signalling pathway has been reported to arbitrate the transcription pathways of a variety of cytokines in various human cancers, including BC, resulting in the regulation of cell proliferation, migration, invasion, apoptosis, survival, immune response and other biological processes.11, 12, 13. This evidence concerns the gene SOAT1 and breast cancer.