We found that the increased expression of MTHFD2 was significantly correlated with T stage (p < 0.001; Figure 2A), M stage (p = 0.028; Figure 2C), histologic grade (p < 0.001; Figure 2D), tumour subtype (p < 0.001; Figure 2E) and pathologic stage (p < 0.001; Figure 2F). This evidence concerns the gene MTHFD2 and neoplasm.