TGFB1 and cancer: To explore the potential effects of the copper chelator with TGF-β signaling, we interrogated our RNA-Seq data obtained from MDA-MB-231 (4 mM TEPA, for 8 and 24 h), SH-SY5Y (2 mM TEPA for 24 h) and DIPG010 (8 mM TEPA for 24 h) cancer cell lines.