Compared to patients with AD, patients with RHI/TES had lower plasma GFAP (p = 0.007, d = 0.68), higher plasma IL-6 (p = 0.007, d = 0.68), and did not differ in plasma NfL (p = 0.91, d < 0.10). The gene discussed is GFAP; the disease is Alzheimer disease.