Compared to controls, early and late AD cases had significantly lower levels of plasma sCR1 (15.29 ng/ml EOAD, 15.32 ng/ml LOAD, 16.74 ng/ml control; p = 0.031, Fig. 1C) and FH (353.7 μg/ml EOAD, 359.7 μg/ml LOAD, 382.3 μg/ml control, p < 0.05, Fig. 1E). The gene discussed is FH; the disease is Alzheimer disease.