Higher surface expression of CD86 (aOR 1.017, 95% CI 1.001 - 1.032, p = 0.033) on intermediate monocytes associated with the presence of lung cavitation, while higher expression of transitional monocytes (aOR 0.944, 95% CI 0.892 - 0.999, p = 0.047) associated with the absence of lung cavitation in the multivariable model.<h4>Conclusion</h4>These data provide valuable insight into the heterogenous role of monocyte and dendritic cells in TB and HIV infections. The gene discussed is CD86; the disease is tuberculosis.