NFKB1 and oral lichen planus: Among these treatments, corticosteroids are the gold standard treatment for OLP due to their anti-inflammatory and immunomodulatory actions through different mechanisms, including decreased leukocyte exudates into inflamed areas through the inhibition of vasodilation and vascular permeability, repressed transcription of many genes encoding proinflammatory cytokines, including NF-κB, suppressed adhesion molecules expression, such as ICAM-1 and VCAM-1, and regulation of Th1 responses and autoimmunity through their direct effect on T cells with stimulation of IL10 secretion [12].