AKT1 and neoplasm: PI3K/AKT signaling has been identified to play a central role in tumor cell proliferation and cellular viability; thus, to elucidate the underlying mechanisms of the anti-tumor effect of NVS-ZP7-4, we further investigated the effects of NVS-ZP7-4 on the PI3K/ AKT pathway in HCCLM3 and Huh7 cells through western blotting.