TNF and familial dilated cardiomyopathy: The detection of serum markers, such as increased inflammatory mediators (TNFα, isoprostanes, IL-6, and C-reactive protein), elevated fibrotic markers (TGFβ1 and IGFBP7) and decreased antioxidant markers (leptin, adiponectin, and bilirubin), can also provide a basis for the early diagnosis and treatment of DCM [12].