ZIC2 and nasopharyngeal carcinoma: To investigate whether JUNB regulates the secretion of MCSF induced by ZIC2 overexpression, we detected the expression of MCSF in NPC cells treated with the JUNB-specific siRNA and inhibitor T5224 and found that the expression of MCSF was significantly decreased by ELISA (Fig. 5A), suggesting JUNB is involved in MCSF secretion in NPC cells.