RET and lung carcinoma: Molecular testing with a targeted panel of 8 lung cancer-associated driver genes (Burning Rock Biotech, Guangzhou, China) detected a novel PIBF1-RET (P16:R12) fusion (abundance 10.3%), which putatively encodes a gene in which the first 16 exons of PIBF1 was concatenated to RET exon 13 and its downstream sequence, retaining the RET kinase domain (Fig. 2A and B).