FADS2 and adrenal cortex adenoma: FADS2 expression was analyzed in nontumorous adrenocortical tissue, nonfunctioning adrenocortical adenomas (hormonally inactive), and aldosterone-producing adenomas (Conn adenomas) and was found to be significantly higher in aldosterone-producing adenomas compared to both, nontumorous adrenocortical tissue and nonfunctioning adenomas (Fig. 7A).