CXCL16 and neoplasm: In addition, IFNγ-driven increased expression of chemokines in tumors of Dox-treated mice (Fig. 3C; Supplementary Fig. S3F), such as CCL2, CCL3, CCL5, and CXCL16 has been associated with enhanced recruitment of CD8+ T cells to tumors and reduced tumor progression (23–25).