CRP and bacterial infectious disease: There is a large body of evidence suggesting that CRP is an effective marker for distinguishing bacterial from non-bacterial infection, though most of these studies took place in high-resource settings (Alcoba and co., Switzerland, 2017, and Zhao and co., Beijing, 2020), and very few considered malaria (Lubell and co., Cambodia, 2015 and Mahende and co., Tanzania, 2017).