CARM1 and Miyoshi myopathy: In our study, we found that knockdown of CARM1 in MM cell lines affected the expression of p53 at the mRNA and protein levels, while a significant decrease in the dimethylation level of BAF155 (the direct substrate of CARM1) by Western blotting assay, indicating that our constructed vectors expressing two different small hairpin RNAs (shRNAs) effectively targeted CARM1 and affected methyl transfer.