To investigate whether knockdown of KIAA0930 affects cytokine/chemokine secretion in vitro, we first analyzed cytokine/chemokine secretion from various cancer cell lines using ELISAs and found that the cytokine/chemokine secretion profiles were completely different among the cell lines (Figure 4A–4C and Supplementary Figure 5A–5C; compare the left column in each Figure). This evidence concerns the gene KIAA0930 and cancer.