CDC42 showed distinct expression levels in glioma about their clinicopathological characteristics, such as IDH mutation status, MGMT promoter methylation status, 1p/19q codeletion status, pathological classification, and the WHO grade, which were analyzed in the TCGA database (Figure 3A) and validated in the CGGA database (Figure 3B). The gene discussed is MGMT; the disease is central nervous system cancer.