The results showed that E2F TARGETS, G2M CHECKPOINT, MYC TARGETS V1 and MTORC1 SIGNALING were significantly positively enriched in both databases in CML patients with low CMTGSS, while IL6 JAK STAT3 SIGNALING, TNFA SIGNALING VIA NFKB, INTERFERON GAMMA RESPONSE and INTERFERON ALPHA RESPONSE were significantly negatively enriched, suggesting that low CMTGSS is associated with enhanced CML cell proliferation and suppression of immune responses. This evidence concerns the gene IL6 and chronic myelogenous leukemia, BCR-ABL1 positive.