Future studies should prioritize mechanistic research to elucidate the role of YAP-1 in the development of ocular surface squamous neoplasia (OSSN) by examining additional essential factors within the Hippo pathway, such as MST1/2, SAV1, LATs1/2, and TAZ, among others, as this is the main limitation in our study. This evidence concerns the gene LATS1 and conjunctival squamous cell carcinoma.