SMARCA2 and adrenal cortex carcinoma: Mutations in chromatin remodeling genes are frequently reported (SMARC1, SMARCA2, ARID1A, ARID1B, CREBBP, EP300), and this class of genes has also been shown to be downregulated in ACC (SMARCA4, SMARCB1, SMARCC1, SMARCC2, ARID1, and PBRM1) (64, 71, 73, 74).