On the other hand, there are subgroups of patients with ACC that do not express MYB/MYBL1 express KLF4, FOXO1, JUNB, FOSB, VGLL3 or ERBB3, CTNNB1 and SOX4. The expression of ERBB3, CTNNB1 and SOX4 was associated with a survival of less than 10 years in patients with ACC (78). This evidence concerns the gene CTNNB1 and adrenal cortex carcinoma.