ENO2 and small cell lung carcinoma: Surprisingly, we found that the multi-biomarker panel (7MP) combining the conventional markers NSE, squamous cell carcinoma antigen (SCC), pro-gastrin-releasing peptide (Pro-GRP), and 4MP could significantly improve the performance of 4MP in differentiated LADC, SQCLC, and SCLC, which may contribute to achieving personalized precision treatment.