The mRNA expression (Fig. 3A) from high to low was as follows: PLC (9.68-fold, P = 0.0003), HCC-LM3 (6.78-fold, P = 0.0044), HuH-7 (5.31-fold, P = 0.0013), and Hep G2 (2.47-fold, P = 0.0049). This evidence concerns the gene HSPG2 and hepatocellular carcinoma.