FOXD3 and non-small cell lung carcinoma: Moreover, NSCLC cells can release exosomes containing considerable lncRNA FOXD3-AS1, which is able to stimulate the PI3K/AKT pathway of recipient cells through binding to ELAV-like RNA-binding protein 1 (ELAVL1), resulting in the promoted NSCLC cell proliferation and invasion and the repressed 5-fluorouracil-induced apoptosis 87.