Compared with certain NSCLC biomarkers, including CEA, CYFRA21-1and CA-125, exosomal LINC00917 has better diagnostic value for patients with advanced NSCLC (Stage III/IV) with an AUC of 0.907, suggesting that exosomal LINC00917 tends to be a specific biomarker for detecting patients with advanced NSCLC. The gene discussed is LINC00917; the disease is non-small cell lung carcinoma.