However, we found that the ALDH2 levels were downregulated in the oral cavity cancers (n = 23, 14.28 ± 16.51) compared to healthy tissues (P = 2.15×10-2), whereas no significant difference compared to laryngeal cancer (n = 72, 27.11 ± 21.61; P = 7.49×10-1) (Fig. 3D). This evidence concerns the gene ALDH2 and oral cavity cancer.