GRPR and neoplasm: IRDye800CW and RM26 (a nine‐amino‐acid bombesin antagonist analog D‐Phe‐Gln‐Trp‐Ala‐Val‐Gly‐His‐Sta‐Leu‐NH2) have made great achievements in tumor‐targeting imaging26, 27; we therefore developed and proofed a novel GRPR targeting probe using RM26 in combination with the IRDye800CW fluorophore for NIR‐II imaging guided neurosurgery.