IL-6 plasma levels (Figure 1D) in mice with LPS-induced glomerulonephritis treated with fucoidan were near-significantly (p = 0.05) decreased, whereas treatment with unstimulated HSglx, LPS HSglx or sulodexide showed a trend to decrease plasma IL-6 levels, which was in part mirrored in the cortical mRNA expression levels for IL-6 (Figure 2B). This evidence concerns the gene IL6 and glomerulonephritis.