pRD can also present as chronic infections with Cytomegalovirus (CMV) or Epstein-Barr virus (EBV) accompanied by γδ T cell expansion (26, 27), idiopathic CD4+ T cell lymphopenia (ICL) (28), common variable immunodeficiency (CVID) (29–31), and selective IgA deficiency (SIgAD) (32). Here, CD4 is linked to common variable immunodeficiency.