As GAS6 is a key tumor cell survival factor and a common ligand for AXL, MERTK, and TYRO3 [3], our data imply that GAS6-CAR-T cells can recognize and kill cells overexpressing any of the TAM proteins, and ability to kill CSCs is more dependent on the higher expression of TYRO3 and MERTK than AXL in contrast to parental cell lines. Here, TYRO3 is linked to neoplasm.