One of these terms was Y-linked inheritance and the other was gonosomal inheritance, which contains the genes: DDX3Y, KDM5D, CDKL5, USP9Y, ROM1, KDM6A. Moreover, among the 16 enriched pathways, 12 genes were enriched in transcriptional misregulation in cancer, accounting for 4.4%; 9 genes were enriched in the neuroactive ligand-receptor interaction pathway, accounting for 3.3%; and 8 genes were enriched in cell adhesion molecules pathway, accounting for 2.93% (Table. This evidence concerns the gene KDM5D and cancer.