To identify whether these signaling pathways mediate the function of the circSLC4A7/HSP90 complex in GC, the expression levels of their target genes (NOTCH1, β-catenin, HES6, HEY1, HES1, and NRARP for NOTCH signaling; MYC, CCND2, and FN14 for Wnt signaling; VEGF, HIF1A, BIRC5, MMP2 for NF-κB signaling; BMI1, GLI1, PATCHED, GLI3 for Sonic Hedgehog signaling; YES1 and YAP1 for Hippo-Yap signaling) were measured by qRT-PCR assay. The gene discussed is NOTCH1; the disease is gastric cancer.