ATG5 and hepatocellular carcinoma: We also report a new mechanism by which hepatocytic exosomes enhance protective autophagy in HCC cells via exosomal circTGFBR2 and the circTGFBR2/miR-205-5p/ATG5 axis, contributing new evidence for the crosstalk between hepatocytes and HCC cells and a potential therapeutic target for HCC treatment.