The western blotting assay showed that coculturing with Exo-Ts could significantly increase LC3B lipidation and decrease p62 accumulation in Hep3B and Huh-7 cells, suggesting that exosomes from starved THLE-2 cells were capable of enhancing autophagy in their target HCC cells (Fig. 2A). The gene discussed is MAP1LC3B; the disease is hepatocellular carcinoma.