A single-center retrospective cohort study at a specialized center in Germany reported an increase in the rate of late HIV diagnoses during the pandemic (83%; 34/41) compared with that seen pre-pandemic (59%; 20/34); increased incidences of late diagnosis (p = 0.020) and lower CD4 counts (< 350 cells/μL [p = 0.037]; < 200 cells/μL [p = 0.022]) were associated with the ongoing COVID-19 pandemic in this study [39]. This evidence concerns the gene CD4 and COVID-19.