We did not observe significant changes in different subsets of CD4+ (CM-Panc1; Fig. 1A–E column 1–2, CM-MiaPaca2; Supplementary Fig. 1C) and CD8+ Tnaiv, Teff, Tem, Tcm and Treg compared to PBMCs from HD cultured alone (Fig. 1F–I, column 1–2). Here, CD8A is linked to Huntington disease.