The adjusted HR for lymph node metastasis (≥ 4 vs. 0) was 3.00 (95% CI 1.94 – 4.66, p < 0.001), which was higher than the adjusted HR of 1.58 for Ki67 expression (95% CI 1.08 – 2.30, p = 0.017). The gene discussed is MKI67; the disease is metastatic malignant neoplasm in the lymph nodes.