TFE3 and neoplasm with perivascular epithelioid cell differentiation: The TFE3-rearranged PEComas harbor TFE3 gene fusions, which correlate with a strong nuclear immunoreactivity for TFE3 (Argani et al. 2010; Malinowska et al. 2012); approximately 15% cases show strong nuclear staining for TFE3 (Bonetti et al. 2001).