Mutations in proteins localized to the IPM such as interphotoreceptor retinoid-binding protein, IRBP, are involved in inherited retinal dystrophies (IRDs) (den Hollander et al. 2009; Li et al. 2013; Sato et al. 2013; Markand et al. 2016). Here, RBP3 is linked to respiratory distress syndrome in premature infants.