In addition, Oxidative phosphorylation, HIF-1 signaling pathway, TGF-beta signaling pathway, Wnt signaling pathway, Apoptosis-associated oxidative stress and cell death-related pathways, MAPK signaling pathway, p53 signaling pathway, PI3K-Akt signaling pathway Breast cancer, and JAK-STAT signaling pathway of cancer-related signaling pathways were also significantly enriched (Figure 2F). The gene discussed is AKT1; the disease is breast cancer.