The percentages of CD4-IFNγ, CD4-Treg, CD4-ISG15, and CD8-GZMB were higher in TB than in LTBI and TBN, whereas CD4-naive, CD4-IL7R, CD8-ITGA1, and CD8-CCR6 showed higher percentages in LTBI (Figure 6(c), Figure S4B). The gene discussed is ISG15; the disease is tuberculosis.