Missense variants in the Arf1 regulator gene AGAP1 and heterozygous deletions in the 2q37.2 region that span this gene (Leroy et al., 2013) are associated with autism spectrum disorder (Cukier et al., 2014; Pacault et al., 2019) and cerebral palsy (Chopra et al., 2022; Jin et al., 2020; van Eyk et al., 2019). This evidence concerns the gene AGAP1 and autism spectrum disorder.