CXCL8 serves as a chemotactic molecule for monocytes and neutrophils (Zhang and Chen, 2002) and plays an important role in inflammatory diseases such as rheumatoid arthritis, IBD or psoriasis (Seitz et al., 1991; Schröder et al., 1992; Grimm et al., 1996). This evidence concerns the gene CXCL8 and inflammatory bowel disease.