OGA and neuroblastoma: Interestingly, ERK signaling was predicted to be significantly upregulated via Ingenuity Pathway Analysis (IPA) of RNA sequencing data in SH-SY5Y neuroblastoma cells after increased O-GlcNAcylation from long-term treatment with O-GlcNAcase (OGA) inhibitor Thiamet-G (TMG) (Tan et al., 2017).