Univariate logistic regression analysis showed that the odds ratio (OR) of PT 1.756, 95% CI: (1.383–2.230), P < 0.001; the OR of PLT 0.994, 95% CI: (0.990–0.998), P < 0.001; the OR of ALB 0.948, 95% CI: (0.910–0.987), P = 0.01; the OR of ALT 1.008, 95% CI: (1.003–1.014), P = 0.003; the OR of AST 1.011, 95% CI: (1.002–1.019), P = 0.014; the OR of GGT 1.011, 95% CI: (1.003–1.018), P = 0.005; the OR of ALP 1.010, 95% CI: (1.002–1.017), P = 0.01; and the OR of HBV-DNA 1.332, 95% CI: (1.123–1.579), P = 0.001, which was associated with significant liver inflammation. The gene discussed is ALB; the disease is Hepatitis.