MAVS and liver dysplastic nodule: In a recent study, to assess the effect of gut barrier damage on renal injury in diabetic conditions, investigators induced DN in wild-type and mitochondrial antiviral signalling protein (MAVS)-knockout mice by unilateral nephrectomy and streptozotocin treatment and found that MAVS knockout diabetic mice exhibited more severe glomerular and tubular injury than wild-type diabetic mice.