Furthermore, AXL overexpression in colorectal adenocarcinoma as compared to normal colon tissues was demonstrated by IHC in tissue microarray resection specimens of primary tumors collected from 509 patients with colorectal adenocarcinoma (stage I-IV) at the National University Hospital of Singapore between 1990 and 1999 (42). This evidence concerns the gene AXL and colorectal adenocarcinoma.