To examine the role of RKIP in two widely studied human breast cancer cell lines: MCF-7 and MDA-MB-231, we collected two publically available datasets in which the status of RKIP was experimentally reversed: knockdown in MCF-7 and overexpression in MDA-MB-231 (Figure 2A) (16, 17). The gene discussed is PEBP1; the disease is breast carcinoma.