HDL-C concentrations (z = 2.890, p = 0.012) decreased, and ALP concentrations (z = −2.581, p = 0.030) increased in the SVD group; Hb (t = 2.698, p = 0.020), ChE (z = 3.073, p = 0.006), and HDL-C (z = 3.173, p = 0.005) concentrations decreased, and hs-CRP (z = −3.652, p = 0.001) and ALP (z = −3.420, p = 0.002) concentrations increased in the PVD group compared with the ND group. The gene discussed is GSTM1; the disease is snowflake vitreoretinal degeneration.