Third, only patients who received IVT and collected blood routine examination at three time points were included in our analysis, so we were unable to investigate the effect of NLR in different populations with IVT, endovascular or standard stroke care without reperfusion treatment, and compare the predictive value of NLR versus other inflammatory biomarkers, such as CRP, IL‐6, and TNF‐alpha, in this population. This evidence concerns the gene CRP and stroke disorder.