The results of univariate analysis were as follows: Patients in the CE group showed a higher median NIHSS on arrival, a higher frequency of AF, a lower median HbA1c, a higher median BNP, a higher median D‐dimer, a shorter median last‐known‐well time to perfusion imaging time, and a lower median DWI‐ASPECTS than patients in the ICAS‐LVO group (Table 1). This evidence concerns the gene NPPB and atrial fibrillation.