LOXL4 and neoplasm: A study by Tan et al. illustrated this phenomenon in the context of hepatocarcinogenesis, where Lysyl oxidase-like 4 (LOXL4), secreted by tumor cells and predominantly localized in hepatic macrophages through exocytosis, catalyzes the conversion of amine groups, resulting in the generation of H2O2 and ammonia as byproducts in a copper-dependent manner.